[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 8, Issue 2 (3-2021) ::
JBRMS 2021, 8(2): 20-26 Back to browse issues page
Effects of tetracycline and Myrtus communis extract on the treatment of recurrent aphthous ulcers: A comparative study
Leila Rajaei-Behbahani , Farid Abbasi, Maryam-Sadat Sadrzadeh-Afshar , Sara Rajaei-Behbahani, Shahla Afshar
Oral and Maxillofacial Medicine Specialist, Tehran, Iran , sadrzadehafsharmaryamsadat@gmail.com
Abstract:   (145 Views)
Introduction: It is widely accepted that recurrent aphthous stomatitis (RAS) is the most common recurrent oral ulcer. Since none of the various symptomatic therapies recommended for painful periods can affect the etiology of the disease, the goal is only to reduce the severity of the pain, irritation, and duration of the ulcers. The purpose of this study was to compare the effects of tetracycline and Myrtus communis extract (Myrtex) on the treatment of RAS.
Materials and Methods: The patients (n=54) enrolled in the study consisted of two groups of 26 and 28 people who received tetracycline and Myrtex, respectively. The case group received Myrtex solution and the control group received 250-mg tetracycline capsules. The patients in both groups kept the drug on the ulcer for 30 seconds four times a day. They answered the visual analogue scale (VAS) on days 0, 2, and 6 and were clinically examined to check any chenges in ulcer size and healing.
Results: According to VAS analysis, the pain and irritation levels in the Myrtex group were 34.8% less than in the tetracycline group (P<0.02). The ulcer size was 40% higher on the second day in the Myrtex group than in the tetracycline group, which was statistically significant (P<0.02), but the ulcer size changes on the sixth day of follow-up were not statistically significant (P<0.15).
Conclusion: According to the study, the administration of Myrtex is more effective in reducing the severity of pain and irritation and improving the quality of life. Therefore, it is recommended to prescribe Myrtex (Myrtex 5%) on the basis of the mentioned method for the treatment of minor aphthous.
Keywords: Recurrent aphthous stomatitis, Tetracycline, Myrtus communis extract, Visual analogue scale, Ulcer duration
Full-Text [PDF 239 kb]   (36 Downloads)    
Type of Study: Research | Subject: Dentistry
Received: 2020/02/5 | Accepted: 2020/05/13 | Published: 2021/03/2
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Rajaei-Behbahani L, Abbasi F, Sadrzadeh-Afshar M, Rajaei-Behbahani S, Afshar S. Effects of tetracycline and Myrtus communis extract on the treatment of recurrent aphthous ulcers: A comparative study. JBRMS. 2021; 8 (2) :20-26
URL: http://jbrms.medilam.ac.ir/article-1-494-en.html


Volume 8, Issue 2 (3-2021) Back to browse issues page
مجله ی تحقیقات پایه در علوم پزشکی Journal of Basic Research in Medical Sciences
Persian site map - English site map - Created in 0.18 seconds with 30 queries by YEKTAWEB 4286