Journal of Basic Research in Medical Sciences
مجله ی تحقیقات پایه در علوم پزشکی
Journal of Basic Research in Medical Sciences
Medical Sciences
http://jbrms.medilam.ac.ir
1
admin
2383-0506
2383-0972
doi
en
jalali
1395
3
1
gregorian
2016
6
1
3
3
online
1
fulltext
en
Evaluating the effect of exercise and nutrition on bone density in rats
Medical Anatomy
Medical Anatomy
پژوهشي
Research
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<p style="text-align: justify;"><strong>Introduction:</strong> The aim of this research was to study the effect of a 6-week supplemented diet on increasing bone density by measuring calcium, phosphorus and bone mineral density (BMD) in male rats.</p>
<p style="text-align: justify;"><strong>Materials and methods:</strong> In this experimental study, 24 Wistar male rats, aged between 15 and 20 days, were selected. The rats were randomly divided into 3 groups: immune system supplement (ISS), ISS plus exercise and control. Daily swimming was performed by time-increasing (starting from ten minutes and ten minutes was added each day and was fixed at sixty minutes). Supplements strengthening the immune system containing calcium and phosphorus were given to rats (5g/kg/day). After six weeks, BMD was measured using bone densitometer. Animals were anesthetized with ketamine and blood samples were gathered in order to separate their serum. The serum samples were used to measure calcium, phosphorus by the ELISA method.</p>
<p style="text-align: justify;"><strong>Results:</strong> The results showed that in both groups (ISS plus exercise and ISS), BMD was higher than the control group. The highest level of calcium, phosphorus and BMD was seen in the group whose members were ISS plus exercise group. In contrast, the least amount of the mentioned markers was reported in the control group.</p>
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<p dir="ltr" style="text-align: justify;"><strong>Conclusion:</strong> The results indicate a small but positive effect of ISS on whole body BMD in male rat; also results indicate the combination of exercise and proper nutrition was more effective on increasing the bone density in comparison with the proper nutrition sedentary group.</p>
Calcium, BMD, Phosphorus, Exercise
15
20
http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-65-2&slc_lang=en&sid=1
Fatemeh
Piri
piri1988@yahoo.com
10031947532846001899
10031947532846001899
No
Department of Anatomy, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran
Afra
khosravi
afrakhosravi@yahoo.co.uk
10031947532846001900
10031947532846001900
No
Department of Immunology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran
Siamak
Derakhshan
siamakderakhsha@yahoo.comn
10031947532846001901
10031947532846001901
No
Department of Nuclear Medicine, Faculty of Medicine, Kourdestan University of Medical Sciences, Kourdestan, Iran
Kourosh
Sayehmiri
koroushsayehmiri@yahoo.com
10031947532846001902
10031947532846001902
No
Department of Epidemiology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran
Ardeshir
Moayeri
moayeri46@yahoo.com
10031947532846001903
10031947532846001903
Yes
Department of Anatomy, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran