en Medical physics Medical physics پژوهشي Research <span style="font-size:9pt"><span minion="" pro="" style="font-family:"><b>Introduction</b>: The early diagnosis of pulmonary embolism (PE) is crucial in improving patient outcomes and reducing mortality rates. Computed tomographic pulmonary angiography (CTPA) is the gold standard method for the diagnosis of PE. Evaluating the effectiveness of CTPA in detecting PE is particularly significant, as a suboptimal CTPA procedure could lead to severe morbidity and mortality for undiagnosed or mismanaged PE patients. In this study, the diagnostic yield of CTPA for the diagnosis of PE was evaluated.</span></span><br> <span style="font-size:9pt"><span minion="" pro="" style="font-family:"><b>Materials & Methods</b><b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">: </span></span></b>In this retrospective cross-sectional study, the electronic records of subjects suspected of having PE were surveyed from the years 2021 to 2023 at two tertiary care hospitals. Demographics, clinical manifestations, comorbidities, medical histories, and the confirmed diagnoses of the patients were retrieved. For each patient, the presence, site, and location of pulmonary embolism on CTPA scans were registered.<span lang="FA" dir="RTL" style="font-family:"Times New Roman","serif""></span></span></span><br> <span style="font-size:9pt"><span minion="" pro="" style="font-family:"><b>Results</b><b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">: &nbsp;</span></span></b>The health records of 1,428 patients were reviewed, and after applying the exclusion criteria, 224 patients with PE were included in the study. One hundred and six of the patients (with a male sex ratio of 47.3%) were male, and their average age was 52.23&plusmn;16.99 years. The results showed that the diagnostic yield of the CTPA approach was 35.71% (95% CI: 29.44% - 41.98%).</span></span><br> <span style="font-size:9pt"><span minion="" pro="" style="font-family:"><b>Conclusion</b><b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">: &nbsp;</span></span></b>The results revealed that CTPA has a limited diagnostic yield, and planning to minimize errors and problems in the radiological data obtained from patients improves the diagnostic performance of this method. Continuous monitoring of CTPA performance, training healthcare professionals, and using clinical decision support tools could significantly impact the diagnosis of PE patients</span></span> Pulmonary embolism, Diagnostic yield, Computed tomographic pulmonary angiography, Computed tomography, Thoracic imaging, CTPA 9 18 http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-546-5&slc_lang=en&sid=1 Seyed Salman Zakariaee salman_zakariaee@yahoo.com 10031947532846008566 10031947532846008566 Yes Non-Communicable Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran Abbas Ghaysouri gheisoori8491@yahoo.com 10031947532846008567 0009-0009-7701-7170 No Department of Internal Medicine, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran Shahab Abdi sh.abdiaa@gmail.com 10031947532846008568 0009-0004-6611-4825 No Department of Radiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran