en Pediatrics Pediatrics پژوهشي Research <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:14.0pt"><span style="line-height:150%"><span arial="" style="font-family:"><span style="letter-spacing:-.2pt">introduction:</span></span></span></span></b> <span style="font-size:14.0pt"><span style="line-height:150%"><span style="color:black">Infant immunisation by intramuscular injection is a painfull procedure for infants. The goal of this study was determine effectiveness of oral sucrose on pain severity in term newborns undergoing </span></span></span>&nbsp;&nbsp;<span style="font-size:14.0pt"><span style="line-height:150%"><span style="color:black">vaccination.</span></span></span><span style="font-size:14.0pt"><span style="line-height:150%"><span arial="" style="font-family:"><span style="color:black"></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:14.0pt"><span style="line-height:150%"><span arial="" style="font-family:">Materials and methods:</span></span></span></b> <span style="font-size:14.0pt"><span style="line-height:150%"><span style="color:black">In this randomized controlled trial 90 term newborns undergoing hepatitis B vaccine injection which performed in Shahid Mustafa Hospital in Ilam, were selected and randomly assigned into three groups: intervention, control and placebo. Then 2 minutes before vaccine injection 2ML 25% sucrose or water for injection was instilled into mouth of infants in intervention or placebo groups, respectively. The newborns of control group didn&#39;t take anything and pain intensity measured by Neonatal Infant Pain Scale (NIPS) during 1-2 min. The collected data were analysed by SPSS18 Software.</span></span></span><span dir="RTL" lang="AR-SA" style="font-size:14.0pt"><span style="line-height:150%"><span b="" style="font-family:" zar=""><span style="color:black"></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="background:white"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:14.0pt"><span arial="" style="font-family:">Results: </span></span></b><span style="font-size:14.0pt"><span style="color:black"></span></span></span></span></span><br> <span style="font-size:12pt"><span style="background:white"><span style="line-height:18.45pt"><span new="" roman="" style="font-family:" times=""><span style="font-size:14.0pt"><span style="color:black">According to the results, there was no significant difference between groups in term of Apgar score, delivery type, sex, head circumstance, weight and height.</span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="background:white"><span style="line-height:18.45pt"><span new="" roman="" style="font-family:" times=""><span style="font-size:14.0pt"><span style="color:black">&nbsp;Comparison of&nbsp;pain&nbsp;severity in two groups, mean and Standard deviation of&nbsp;pain, group that received Sucrose solution had low intensity than&nbsp;sterile water&nbsp;group (3 &plusmn; 1.66 vs. 4.05 &plusmn; 1.23), but this difference was not significant statistically (p=0.78). Comparison of&nbsp;pain&nbsp;intensity in control and intervention groups showed that the&nbsp;pain&nbsp;intensity in control group is higher than intervention and placebo groups (p<0.001).</span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="background:white"><span style="line-height:18.45pt"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:14.0pt"><span arial="" style="font-family:">Conclusion:</span></span></b> <span style="font-size:14.0pt"><span style="color:black"></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""><span style="font-size:14.0pt"><span style="line-height:150%"><span style="color:black">Sweet solution of sucrose can be used as a simple and safe non pharmacological method to reduce the pain following immunization in newborn.</span></span></span></span></span></span></span></span><br> &nbsp; Sucrose,newborn,pain,NIPS 43 48 http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-848-1&slc_lang=en&sid=1 Hamid Taghinejad taghinejad-h@medilam.ac.ir 10031947532846007477 10031947532846007477 No Department of Nursing, Faculty of Nursing and Midwifery, Ilam University of Medical Sciences, Ilam, Iran Zainab Suhrabi suhrabi2007@yahoo.com 10031947532846007478 10031947532846007478 Yes Department of Midwifery, Faculty of Nursing and Midwifery Ilam University of Medical Sciences, Ilam, Iran