[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 9, Issue 2 (3-2022) ::
JBRMS 2022, 9(2): 61-70 Back to browse issues page
The effect of high, low and moderate intensity circuit resistance training on the levels of hepatocyte-derived fibrinogen-related protein 1 (HFREP1) and lipid profile in obese postmenopausal women
Seyedeh Elham Hashemi Jokar , Maghsoud Peeri , Mohammad Ali Azarbayjani
Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran , m.peeri@iauctb.ac.ir
Abstract:   (255 Views)
Introduction: Different hepatokines including the hepatocyte-derived fibrinogen-related protein 1 (HFREP1) are secreted by liver tissue, which can affect the lipid metabolism. The aim of present study was to investigate the effect of 12 weeks circuit resistance training with different intensity on the levels of HFREP1 and lipid profile in obese postmenopausal women.
Materials and Methods: Subjects of the study consisted of 44 postmenopausal women with average age of 56.07 ± 3.18 years old, dividing into the circuit resistance training with low (L-RT), moderate (M-RT), high (H-RT) intensity and the control groups (11 subjects in each group). Training program was conducted for 12 weeks and three session per week. Blood samples collected in pre and post-test stages and the levels of HFREP1 were measured by ELISA method and finally data was analyzed by Graphpad Prism software.
Results: Analysis of HFREP1 data indicated that there were significant differences between different groups (P < 0.001). The results of Bonferroni post hoc-test showed that there was no significant difference between the control and L-RT groups (P > 0.05). However, HFREP1 in M-RT and H-RT groups significantly decreased compared to control group (P < 0.001). In addition, HFREP1 decrease in M-RT and H-RT groups was significant compared to L-RT group (P > 0.05). Lipid profile also improved in all trained groups, which further improvement observed in the H-RT group.
Conclusion: It seems that, higher intensity circuit resistance training is associated with further decrease in the levels of HFREP1, and improving the lipid profile can be attributed partly to downregulation of HFREP-1 levels.
Keywords: Menopause, Circuit resistance training, Hepatokines, HFREP1
Full-Text [PDF 280 kb]   (148 Downloads)    
Type of Study: Research | Subject: Physiology
Received: 2020/04/22 | Accepted: 2020/07/23 | Published: 2022/07/13
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Hashemi Jokar S E, Peeri M, Azarbayjani M A. The effect of high, low and moderate intensity circuit resistance training on the levels of hepatocyte-derived fibrinogen-related protein 1 (HFREP1) and lipid profile in obese postmenopausal women. JBRMS. 2022; 9 (2) :61-70
URL: http://jbrms.medilam.ac.ir/article-1-570-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 9, Issue 2 (3-2022) Back to browse issues page
مجله ی تحقیقات پایه در علوم پزشکی Journal of Basic Research in Medical Sciences
Persian site map - English site map - Created in 0.16 seconds with 29 queries by YEKTAWEB 4447