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:: Volume 12, Issue 1 (1-2025) ::
2025, 12(1): 55-61 Back to browse issues page
Hospital consequences of COVID-19 vaccinated and unvaccinated patients among the Iranian adult population
Fatemeh Mollarahimi-Maleki , Mohammad Shahidi
Department of Community and Family Medicine, School of Medicine, Spiritual Health Research Center, Qom University of Medical Sciences, Qom, Iran , fmollarahimi@gmail.com
Abstract:   (111 Views)
Introduction
Coronavirus disease 2019 is an emerging respiratory infectious disease caused by a strain of the coronavirus family. Vaccination is one of the main ways to control this disease. This study was conducted to investigate the severity of pulmonary involvement and some clinical outcomes in vaccinated and unvaccinated COVID-19 patients.
Materials and methods
This retrospective study was conducted between December 2021 and May 2022 with 200 patients in two groups. Sampling was done as available, and patients with COVID-19 admitted to the hospital were examined. Mann-Whitney u and Chi-square test were used for analysis.
Results
The average age of the studied patients was 59.2 (±17) years, the most common pattern of lung involvement in this study was the GGO pattern. According to the report in the documents, 45 people in the vaccinated group and nine people in the unvaccinated group did not have any lung involvement in CT and the observed difference was statistically significant (P = 0.001).
In terms of oxygen saturation percentage, the lowest level (75%) was observed in the unvaccinated group, also the difference in average hospitalization days between the two groups was statistically significant (P = 0.001).  
 Conclusion
The results of this study showed that the COVID-19 vaccine can effectively reduce the extent and severity of lung involvement and the need for supplemental oxygen in vaccinated patients. To reduce complications from COVID-19, healthcare workers should continue to promote vaccination at recommended doses for all eligible individuals, as it is effective in controlling serious clinical outcomes.
 
Keywords: COVID-19, vaccinated, unvaccinated, outcome, hospital consequences
Full-Text [PDF 900 kb]   (69 Downloads)    
Type of Study: Research | Subject: Infectious diseases
Received: 2024/09/19 | Accepted: 2024/11/6 | Published: 2025/01/12
References
1. References
2. Madhu P, Santhosh D, Kiran M. Comparison study of lung involvement in vaccinated and un vaccinated Covid patients. International Journal of Health and Clinical Research. 2021;4(10):229-33.
3. Mathieu E, Ritchie H, Ortiz-Ospina E, Roser M, Hasell J, Appel C, et al. A global database of COVID-19 vaccinations. Nature human behaviour. 2021;5(7):947-53.
4. Chamorro EM, Tascón AD, Sanz LI, Vélez SO, Nacenta SB. Radiologic diagnosis of patients with COVID-19. Radiología (English Edition). 2021;63(1):56-73. [DOI:10.1016/j.rxeng.2020.11.001]
5. Meter W. Coronavirus Resource Center. 2024 [updated 1.1.2024.
6. Bhadra S, Jiang YS, Kumar MR, Johnson RF, Hensley LE, Ellington AD. Real-time sequence-validated loop-mediated isothermal amplification assays for detection of Middle East respiratory syndrome coronavirus (MERS-CoV). PloS one. 2015;10(4):1-21. [DOI:10.1371/journal.pone.0123126]
7. Wang W, Xu Y, Gao R, Lu R, Han K, Wu G, et al. Detection of SARS-CoV-2 in different types of clinical specimens. Jama. 2020;323(18):1843-4. doi:10.1001/jama.2020.3786
8. Organization WH. Laboratory testing of 2019 novel coronavirus (2019-nCoV) in suspected human cases: interim guidance, 17 January 2020. 2020.
9. Zhai P, Ding Y, Wu X, Long J, Zhong Y, Li Y. The epidemiology, diagnosis and treatment of COVID-19. International journal of antimicrobial agents. 2020;55(5):105955. doi.org/10.1016/j.ijantimicag.2020.105955
10. Xie X, Zhong Z, Zhao W, Zheng C, Wang F, Liu J. Chest CT for Typical Coronavirus Disease 2019 (COVID-19) Pneumonia: Relationship to Negative RT-PCR Testing. Radiology. 2020 Aug 1; 296 (2): E41–5. doi.org/10.1148/radiol.2020200343
11. Shi H, Han X, Jiang N, Cao Y, Alwalid O, Gu J, et al. Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study. The Lancet infectious diseases. 2020;20(4):425-34. doi: 10.1016/S1473-3099(20)30086-4
12. Zarifian A, Nour MG, Rezayat AA, Oskooei RR, Abbasi B, Sadeghi R. Chest CT findings of coronavirus disease 2019 (COVID-19): A comprehensive meta-analysis of 9907 confirmed patients. Clinical Imaging. 2021;70:101-10. doi: 10.1016/j.clinimag.2020.10.035
13. Parry AH, Wani HA, Choh NA, Shah NN, Jehangir M. Spectrum of chest CT manifestations of coronavirus disease (COVID-19): a pictorial essay. Indian Journal of Radiology and Imaging. 2021;31(S 01):S170-S7. doi: 10.4103/ijri.IJRI_303_20
14. Salehi S, Abedi A, Balakrishnan S, Gholamrezanezhad A. Coronavirus disease 2019 (COVID-19): a systematic review of imaging findings in 919 patients. Ajr Am J Roentgenol. 2020;215(1):87-93. doi: 10.2214/AJR.20.23034
15. Yuan X, Huang W, Ye B, Chen C, Huang R, Wu F, et al. Changes of hematological and immunological parameters in COVID-19 patients. International journal of hematology. 2020;112:553-9. doi: 10.1007/s12185-020-02930-w
16. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The lancet. 2020;395(10229):1054-62. doi: 10.1016/S0140-6736(20)30566-3
17. Modi SD, Shah DS, Mundhra KS, Gandhi B, Shah R, Kagathara V, et al. Comparative study of CT severity index and outcome in hospitalised vaccinated and non vaccinated patients of Covid 19 pneumonia. Journal of Radiology and Clinical Imaging. 2021;4(3):93-101. doi: 10.26502/jrci.2809046
18. Serag DM, Selima ER. COVID-19: The Potential Difference in High Resolution Computed Tomography Findings between Vaccinated and Unvaccinated Cases among The Adult Egyptian Population. The Egyptian Journal of Hospital Medicine. 2021;85(2):3883-8. doi: 10.21608/EJHM.2021.205100
19. Dasgupta S, Patil P, Barsode S, Paramshetti B, Akula UK. Retrospective comparative study of clinical profile and pulmonary involvement in unvaccinated and vaccinated individuals diagnosed with COVID-19. Critical Care Innovations. 2023;6(1):17-28. doi:10.32114/CCI.2023.6.1.17.28
20. Havers FP, Pham H, Taylor CA, Whitaker M, Patel K, Anglin O, et al. COVID-19-associated hospitalizations among vaccinated and unvaccinated adults 18 years or older in 13 US States, January 2021 to April 2022. JAMA internal medicine. 2022;182(10):1071-81. doi:10.1001/jamainternmed.2022.4299.
21. Fatima S, Zafar A, Afzal H, Ejaz T, Shamim S, Saleemi S, et al. COVID-19 infection among vaccinated and unvaccinated: Does it make any difference? PloS one. 2022;17(7):e0270485. doi.org/10.1371/journal.pone.0270485
22. Bernal JL, Andrews N, Gower C, Robertson C, Stowe J, Tessier E, et al. Effectiveness of the Pfizer-BioNTech and Oxford-AstraZeneca vaccines on covid-19 related symptoms, hospital admissions, and mortality in older adults in England: test negative case-control study. bmj. 2021;373. doi: 10.1136/bmj.n1088
23. Ruiz-Giardin JM, Rivilla M, Mesa N, Morales A, Rivas L, Izquierdo A, et al. Comparative study of vaccinated and unvaccinated hospitalised patients: A retrospective population study of 500 hospitalised patients with SARS-CoV-2 infection in a Spanish population of 220,000 inhabitants. Viruses. 2022;14(10):2284. doi: 10.3390/v14102284
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Mollarahimi-Maleki F, Shahidi M. Hospital consequences of COVID-19 vaccinated and unvaccinated patients among the Iranian adult population. Journal of Basic Research in Medical Sciences 2025; 12 (1) :55-61
URL: http://jbrms.medilam.ac.ir/article-1-893-en.html


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Volume 12, Issue 1 (1-2025) Back to browse issues page
مجله ی تحقیقات پایه در علوم پزشکی Journal of Basic Research in Medical Sciences
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