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Showing 4 results for Cheraghi
Akbar Azamian Jazi, Hadi Abdi, Mohammad Reza Haffezi Ahmadi, Javad Cheraghi,
Volume 4, Issue 1 (1-2017)
Abstract
Introduction: Cardiac remodeling after myocardial infarction, is associated with progressive ventricular dysfunction and cardiovascular death. The purpose of this study was to examine the effect of endurance exercise training on morphological changes in rat heart tissue following experimental myocardial infarction.
Materials and methods: Rats used in this experiment (8-10 weeks old, 235 ± 5 g body weight) after homogenization according to body weight, were randomly divided to three groups: Healthy (Sham), control (Sedentary) and endurance training groups. Myocardial infarction was induced by subcutaneous injection of isoprenaline (150 mg/kg) in two consecutive days with an interval of 24 hours. Endurance training initiated 2 days after infarction and continued for 4 weeks. In order to assess the necrosis lesion and fibrosis tissue, Hematoxylin–Eosin and Masson's trichrome staining were used, respectively. Data were analyzed by using one-way analysis of variance (ANOVA) at P< 0.05 level.
Results: The results indicated that subcutaneous injection of isoprenaline, induced myocardial infarction in rat heart tissue. Rate of necrotic lesion in the Endurance training group was significantly higher than Sedentary (control) group (P=0.005). Also, the size of fibrosis tissue in the Endurance training group was significantly higher than the sedentary (control) group (P= 0.001).
Conclusion: In general, results of this study showed that 4 weeks of endurance exercise training after myocardial infarction exacerbate tissue injury in rat heart.
Javad Cheraghi, Aref Nooraei, Marzieh Havasi, Salman Soltani,
Volume 9, Issue 2 (3-2022)
Abstract
The new coronavirus (Covid 19) has become a hazardous threat due to its prevalence worldwide. Pregnant women are particularly vulnerable to this infectious disease because their immune system is already slightly compromised during pregnancy, making them more susceptible to viral infections. Therefore, the aim of this study was to investigate abortion due to this disease in different countries of the world. Thirty-six articles were analyzed by searching the web of science, Google Scholar, Pubmed databases for the following keywords: Covid 19 and abortion, Covid 19 and fetus, and Covid 19. Thirteen out of the 36 articles were used, and the rest were excluded from the study due to being unrelated to the subject. Articles related to the new coronavirus and abortion were then carefully studied and analyzed. It was shown in various studies that, due to the infection and immune system compromise during pregnancy, the Coronavirus could play a role in abortion and stillbirth. So, a prognosis of this threat could help pregnant women observe the health protocols during the pandemic more seriously so that they are more protected against being infected.
Mojtaba Cheraghian, Tayyeb Pourfallah, Amir Abbas Sabouri-Dodaran, Mehrdad Gholami,
Volume 9, Issue 3 (6-2022)
Abstract
Introduction: In this research, a new material (Ti2V0.7Cu97.3) was proposed for the target of medical linear accelerators (linacs) to reduce the production of unwanted photoneutrons in the radiotherapy. So, the fluence, dose equivalent and kerma of the photoneutrons were calculated in a soft tissue phantom.
Materials and Methods: The medical linac was the Varian 2100 C/D 18 MV, which its tungsten target was replaced with a new multi-metal target (Ti2V0.7Cu97.3). Desired quantities were computed in a ICRU soft tissue phantom, using the Monte Carlo code MCNPX (v. 2.6).
Results: The ratio of the maximums of fluence, kerma, and dose equivalent of photoneutrons along the central axis of the ICRU phantom with new target rather than tungsten target were 72 %, 59 % and 61 %, respectively. Average of the Ratio of fluence, kerma, and dose equivalent in inner area (distances less than 5 cm from central axis) at different depths of the phantom with new target rather than tungsten target were 78 %, 70 % and 75 %, respectively. Uncertainties at all points were less than 5 % (except for a few points which were less than 10 %).
Conclusion: This work showed that applying Ti2V0.7Cu97.3 alloy for the target of linac, can reduce the produced photoneutrons up to 38 % by an applicable and inexpensive way.
Javad Cheraghi, Aref Nooraei, Marzihe Havasi, Salman Soltani, Saeed Feez Babaei, Mostafa Hajizade,
Volume 10, Issue 1 (1-2023)
Abstract
Introduction: With the outbreak of COVID-19, researchers started their studies on the various aspects of the infection by this newly-emerged virus. In addition to the pulmonary infection routes, some signs were discovered regarding psychological and physiological damages.
Materials and Methods: Our study aimed at collecting the results of the studies around the world on the possible psychological and physiological damages caused by COVID-19 in the neural system. Herein, we gathered 125 related articles up to June 2021 by searching the keywords COVID-19 brain infection, COVID-19 infection disease imaging findings COVID-19, mental health, and COVID-19 in the databases such as Scopus, Pubmed, Web of Science, Google Scholar, and Google. The articles unrelated to the objective of our study were excluded, and finally, 43 articles were used.
Results: In this study, reports indicate an increase in the volume of gray matter in the hippocampus and olfactory lobe and an increase in anisotropy in the white matter in people with the acute form of the disease compared to people without it. Therefore, psychologically, some forms of mental rumination and apathy were confirmed in affected people.
Conclusion: Considering the probable inability of the SARS-COV virus to cross the blood-brain barrier, the reason for the neuropathological lesions and brain encephalopathies has yet to be discerned, and this is a somewhat unknown mechanism
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