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Showing 1 results for Tabatabaei

Moslem Taheri Soodejani, Maryam Kazemi, Seyyed Mohammad Tabatabaei, Mohammad Hassan Lotfi,
Volume 10, Issue 3 (6-2023)
Abstract

Introduction: This study aimed to predict the risk of mortality among COVID-19 patients in the central region of Iran by employing the Charlson Comorbidity Index (CCI), with adjustments made for age in the predictive model.
Materials & Methods: In this cross-sectional study, encompassing all probable, suspicious, and confirmed COVID-19 cases from the onset of the pandemic (55307 individuals), 3415 cases resulting in death were designated as the study group, while the survivors constituted the control group.
Results: The Charlson Comorbidity Index revealed that over 11 percent of all patients had at least one underlying medical condition. Logistic regression analysis indicated a significantly elevated likelihood of mortality among patients with comorbidities. Specifically, individuals with a CCI score of 6 or higher were more than twice as likely to succumb to the virus compared to those without underlying diseases. Those with a score of 6 or more exhibited the highest odds ratio (OR 2.4; 95% CI 1.3-4.5).
Conclusion: The study findings underscore the heightened vulnerability of individuals to COVID-19 mortality, particularly among the elderly with pre-existing health conditions. The coexistence of age and comorbidities substantially increased the risk of death due to COVID-19 in this population. Consequently, targeted interventions and focused care strategies may be crucial for this high-risk demographic in pandemic management efforts.


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مجله ی تحقیقات پایه در علوم پزشکی Journal of Basic Research in Medical Sciences
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