|
|
|
 |
Search published articles |
 |
|
Showing 3 results for Abortion
Mohammad Reza Chaechi Nosrati, Bahar Shemshadi, Parviz Shayan, Shahrokh Ranjbar Bahadori, Ali Eslami,
Volume 7, Issue 4 (9-2020)
Abstract
Introduction: Sheep farming is one of the most important economic aspects of the livestock industry in Gilan province, Iran. Toxoplasmosis is a prevalent zoonotic disease and a major cause of abortion, congenital infection, and stillbirth in animals and humans. Previously, it was assumed that sheep are mostly infected with Toxoplasma gondii (T. gondii) after birth. Nevertheless, recent studies have shown that T. gondii congenital transmission is more prevalent than previously speculated. Therefore, determining the genotypes of this parasite in the intermediate host plays an important role in human infections and prevention programs. This cross-sectional study aimed to determine the T. gondii genetic diversity in aborted ovine fetuses during the lambing season (2018-2019) in Gilan province, Iran.
Materials and Methods: Molecular detection of T. gondii was performed in 44 brain tissue samples, collected from aborted ovine fetuses, using a nested polymerase chain reaction (nested-PCR) assay, to target the GRA6 gene. Also, the nested-PCR products belonging to the GRA6-positive samples underwent genotyping with the help of Tru1I (MseI) restriction enzyme using the PCR-restriction fragment length polymorphism (PCR-RFLP) method to classify strains into one of the three major lineages of T. gondii.
Results: The results revealed infection in 30 (68.18%) out of 44 brain samples of aborted ovine fetuses, based on the nested-PCR assay with GRA6 gene. Also, the PCR-RFLP results demonstrated the predominance of type II T. gondii in all of the isolates.
Conclusion: Overall, the present results revealed the high incidence of T. gondii infection through congenital transmission.This is the first molecular detection and genotyping of T. gondii in ovine aborted fetuses in Gilan Province, Iran.
Javad Cheraghi, Aref Nooraei, Marzieh Havasi, Salman Soltani,
Volume 9, Issue 2 (3-2022)
Abstract
The new coronavirus (Covid 19) has become a hazardous threat due to its prevalence worldwide. Pregnant women are particularly vulnerable to this infectious disease because their immune system is already slightly compromised during pregnancy, making them more susceptible to viral infections. Therefore, the aim of this study was to investigate abortion due to this disease in different countries of the world. Thirty-six articles were analyzed by searching the web of science, Google Scholar, Pubmed databases for the following keywords: Covid 19 and abortion, Covid 19 and fetus, and Covid 19. Thirteen out of the 36 articles were used, and the rest were excluded from the study due to being unrelated to the subject. Articles related to the new coronavirus and abortion were then carefully studied and analyzed. It was shown in various studies that, due to the infection and immune system compromise during pregnancy, the Coronavirus could play a role in abortion and stillbirth. So, a prognosis of this threat could help pregnant women observe the health protocols during the pandemic more seriously so that they are more protected against being infected.
Shima Hashemi , Ashraf Direkvand Moghadam , Kourosh Sayehmiri , Mirhadi Mousavi , Hamzeh Ahmadi , Monireh Azizi , Khairollah Asadollahi ,
Volume 11, Issue 2 (4-2024)
Abstract
Introduction: Abortion, a common pregnancy complication, is influenced by multifaceted reproductive, economic, social, and cultural factors. This study investigates abortion determinants among pregnant women in Khorramabad, Iran, from September 2020 to March 2021.
Material & Methods: This case-control study involved 416 pregnant women (208 cases, 208 controls) selected from Khorramabad health centers through census and random sampling during the COVID-19 pandemic. Data on demographics and pregnancy history were collected using a checklist and analyzed with STATA16.
Results: Among the 416 pregnant women, the mean age was 31.00 ± 5.53 years in the control group and 32.27 ± 6.85 years in the case group. Furthermore, 74 (35.58%) mothers in the case group had a diploma, 192 (92.31%) were housewives, and 106 (50.96%) had A+ blood group. The majority of mothers (46.63% in case, 39.42% in control) had an overweight range of pre-pregnancy BMI (25-29.9) (kg/m2). The mean height was 162.97 ± 5.30 in the control group and 160.86 ± 5.39 in the case group. Multiple regression logistic analysis confirmed significant associations between abortion and mother's age (OR=4.67, 95%CI=1.11-19.62), previous cesarean delivery (OR=4.33, 95%CI=1.94-9.66), not taking folic acid pills during pregnancy (OR=14.92, 95%CI=6.25-35.61), low income (OR=7.00, 95%CI=2.02-24.35), not smoking (OR=0.28, 95%CI=0.08-0.94), and absence of pre-diabetes (OR=0.13, 95%CI=0.03-0.47) (p < 0.05). No significant relationships were found between abortion and other studied risk factors.
Conclusion: Older mothers with lower income levels are more likely to experience abortion. Additionally, factors such as pre-existing pre-diabetes, previous cesarean deliveries, smoking, lack of folic acid supplementation, and maternal infections are identified as risk factors for abortion. Providing education, healthcare, and continuous support from healthcare workers can promote safe pregnancies, reduce the risk of abortion, and enhance maternal and child health outcomes.
|
|
