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Showing 4 results for Hiit
Golbano Blori, Hossein Abednatanzi, Hojjat Allah Nikbakht,
Volume 9, Issue 2 (3-2022)
Abstract
Introduction: Aging causes changes in metabolic, cardiovascular, and neuromuscular functions. By developing aging process, physical activity decreases, which is mainly due to fundamental changes in body composition and lack of angiogenesis for which some indicators of angiogenesis have been found in older male mice. The purpose of this study was to investigate the effect of high-intensity interval training (HIIT) on angiogenesis indices in elderly male rats.
Materials and Methods: The studied sample included 20 elderly male mice, which were randomly divided into two groups of control (n = 10) and experimental (n = 10). The experimental group repeated the HIIT in the specified intervals. The exercises were repeated after two minutes of rest, with 80% of the maximum speed in the first week, 90% in the second week, 100% in the third week, and 110% from the beginning of the fourth week, until the end of the training. To evaluate the research variables (VEGF, FGF21, NO, apelin-13), 3 ml of peripheral blood was drawn from the tail of elderly male mice 72 hours before and after the last session of the training.
Results: Eight weeks of HIIT significantly increased VEGF and NO (P = 0.001). It also increased the FGF and apelin-3 levels significantly (P = 0.0001). No significant change was observed in the control group.
Conclusion: The results of this study showed that eight weeks of HIIT significantly increased angiogenesis levels in elderly male rats. Therefore, HIIT can be used as an appropriate and especially alternative exercise to increase angiogenesis in the elderly individuals.
Elahe Alivais, Sabrieh Amini, Karimeh Haghani, Hori Ghaneialvar, Fatemeh Keshavarzi,
Volume 9, Issue 2 (3-2022)
Abstract
Introduction: High-intensity interval training (HIIT) and moderate-intensity continuous training (MCT) in combination with metformin in diabetic patients is likely to be effective. This research aimed to investigate the possible role of HIIT and MCT training alone and also in combination with metformin on biochemical factors and lipid profiles in diabetic and healthy rats.
Materials and Methods: Sprague-Dawley rats were allocated randomly into nine groups (in each group n = 5). Streptozotocin and nicotinamide were used to induce diabetes in target rats. Special diets were given to all groups of rats and exercise protocol was performed one time per week for 8 weeks. Rats received metformin (200 mg/kg) daily by gavage. The biochemical factors and serum lipid profiles were measured. Data analysis was performed using SPSS software and the significance level was considered at P < 0.05.
Results: The lowest serum glucose and insulin levels among diabetic rats belonged to the diabetic group who received metformin and performed HIIT training (P < 0.05). Diabetic groups that performed HIIT and MCT training compared with the diabetic group that consumed metformin alone had lower HbA1c levels, which this difference was not significant (P < 0.05). The lowest triglyceride level among the treated diabetic groups was in the group that received metformin and performed HIIT training (P < 0.05). The results of HDL, LDL and cholesterol changes were similar to those found for triglyceride. Conclusion: The study showed that both HIIT and MCT exercise, even in the absence of metformin, significantly reduce some biochemical factors and lipid profile levels as well as improve body weight in the diabetic rats under treatment with metformin compared with the diabetic control group.
Zahra Toktam-Barmar, Sadegh Cheragh-Birjandi, Najmeh Rezaeian,
Volume 9, Issue 4 (9-2022)
Abstract
Introduction: Tissue dysfunction might be the result of reactions between free radicals and cell membranes. The purpose of this study was the evaluation of cell vulnerability and assessment of the effect of intense intermittent exercise and curcumin supplementation on apoptotic and antiapoptotic factors in Wistar rats.
Materials and Methods: For the study, 60 adult male Wistar rats were randomly divided to 5 groups (n = 8) of saline, hydrogen peroxide (H2O2), high intensity interval training (HIIT) + oxygenated Water, Curcumin Supplement + Oxygenated Water, and HIIT + Curcumin Supplement + Oxygenated Water. Rats were treated with H2O2 in the amount of 1 mmol/kg of body weight three times a week on even days and curcumin, 150 m
g/kg of body weight, daily. Treadmill running program was performed for 8 weeks. Real-time PCR was applied to assess Bcl-2-associated X protein (Bax) and B-cell lymphoma 2 (Bcl-2) genes expression. Data were analyzed by using the Two-way ANOVA.
Results: The induction of oxidative stress by H2O2 increased expression of Bax, and decreased expression of Bcl-2 in hippocampus of rats (P = 0.0001). HIIT and curcumin supplementation decreased expression of Bax, and increased expression of Bcl-2, Also, decreased the Bax/Bcl-2 ratio (P = 0.0001).
Conclusion: This finding showed that doing HIIT and taking curcumin supplements have been able to decreas oxidative stress, and the effect of both together could further reduce the apoptotic process.
Mohamad Parastesh, Behzad Aria, Erfan Bastan, Abbas Saremi,
Volume 10, Issue 2 (3-2023)
Abstract
Introduction: Endocrine function and metabolic health can be impacted by obesity and overweight. The current study examined how bodyweight high-intensity interval training and calisthenics affected overweight men's cortisol and testosterone serum levels.
Materials and Methods: Thirty-two overweight men (age: 19.5 ± 5.4 year; height: 175.4 ± 4.2 cm; weight: 90.9 ± 7.6 kg) divided into three groups: Calisthenics training (n=12), bodyweight high-intensity interval training (HIIT) (n=12), and control (n=8). The HIIT and calisthenics groups trained three times a week for eight weeks. Ten mL blood samples were collected from the antecubital vein 24 h before and after the training. Testosterone and cortisol serum levels were measured by ELISA technique. ANOVA and Bonferroni were used for data analysis.
Results: The results showed that the serum levels of testosterone in HIIT and calisthenics groups increased significantly, and cortisol decreased compared to the control group (P < 0.05). However, there was no significant difference between the serum levels of testosterone and cortisol in HIIT and calisthenics groups.
Conclusion: Calisthenics and bodyweight HIIT can increase testosterone and decrease cortisol in overweight males.
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