en Medical Anatomy Medical Anatomy گزارش مورد Case report <div dir="ltr"> <p style="text-align: justify;"><strong>Introduction:</strong> Congenital anomalies are a common cause of disability and mortality in newborns and their treatments involves high costs for the society. This study aimed to investigate the prevalence of congenital anomalies and their causes.</p> <p style="text-align: justify;"><strong>Materials and methods:</strong> This research was a descriptive-analytical study and the population included all the newborns in hospitals of the city of Ilam in 2011. Variables of abnormality type, birth status, and medical and genetic illness histories were included into the data collection forms. Data was analyzed through Chi-square tests and Fisher&#39s exact test using SPSS software.</p> <p style="text-align: justify;"><strong>Results:</strong> Of 460 neonates, 5.4 percent (25 cases) had died at birth and 3.7 percent (16 infants) were born with a birth defect. 43.8 percent of malformed babies had a family history. 31.3 % of the malformed babies had genetic syndromes, whose parents had consanguineous marriage. 18.8% of babies with defects in the central nervous system and cardiovascular system showed a similar percentage of disorder. The defect in the urinary system, head and neck each accounted for 12.5 percent.</p> <p style="text-align: justify;"><strong>Conclusion:</strong> This study shows that consanguineous marriages can be the most common genetic cause of genetic syndromes.</p> </div> Congenital malformations, Genetic syndromes, Consanguineous Marriages 41 45 http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-122-1&slc_lang=en&sid=1 Kourosh Sayehmiri delnianoori@gmail.com 10031947532846001879 10031947532846001879 No Research Center for Prevention of Psychosocial trauma, Ilam University of Medical Sciences, Ilam, Iran Mohammad Reza Kaffashian delnianoori@gmail.com 10031947532846001880 10031947532846001880 No Department of Physiology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran Elahe Ranaei delnianoori@gmail.com 10031947532846001881 10031947532846001881 Yes Department of Anatomy, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran