en Clinical microbiology Clinical microbiology پژوهشي Research <p style="text-align: justify;"></p> <div> <p style="text-align: justify;"><strong>Introduction:</strong> <em>Escherichia coli</em> (<em>E.coli) </em>as a main cause of both nosocomial and community-acquired infections in humans have a relative potential to develop resistance. Nowadays, most infections caused by ESBL-producing <em>E.coli</em> (ESBLEC) had mostly been described as nosocomial acquired or nursing home related. In this study, we employed E-test assay to detect antibiotic resistance of <em>E.coli</em> strains and determine MIC of antibiotics.</p> <p style="text-align: justify;"><strong>Materials and methods:</strong> Thirty <em>E.coli</em> strains gathered from Imam Khomeini hospital of Ilam, and cultured on TSB and bacterial suspension prepared by 0.5 &micro;F concentration for E-test. Mueller Hinton agar and E-test strips of <em>Amikacin, Cefepime, Ceftazidime, Ceftriaxone, Gentamicin, Meropenem, Nitrofurantoin, Piperacillin/Tazobactam, Tetracycline, Ticarcillin/ Clavulanic acid, Tobramycin, Trimethoprim</em> were used</p> <p style="text-align: justify;"><strong>Results:</strong> Resistance to <em>Ceftriaxone, Tobramycin, Gentamicin, </em><em>Ticarcillin/ Clavulanic</em><em>, Amikacin were</em> 19.8%, 26.4%, 23.3%, 62.7%, 70.3%, respectively.</p> </div> <p style="text-align: justify;"><strong>Conclusion:</strong> the results indicated, <em>E.coli</em> strains in this study were high sensitivity to <em>Meropenem ,</em><em>Nitrofuratoin, Ciprofloxacin , Ceftazidime, Cefepime</em>.</p> E-test, Antibiotic susceptibility, E.coli, Ilam, Iran 17 21 http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-164-1&slc_lang=en&sid=1 Lida Bimanand lidabimanand@yahoo.com 10031947532846002060 10031947532846002060 No Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam Norkhoda Sadeghifard pakzadi2006@gmail.com 10031947532846002061 10031947532846002061 No Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam Farid Azizi Jalilian sadehifard@gmail.com 10031947532846002062 10031947532846002062 No Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam Hassan Hossainzadegan azizifarid@gmail.com 10031947532846002063 10031947532846002063 No Department of Microbiology, Faculty of Nursing , Maragheh University of Medical Sciences, Iran Sattar Mohammadi Darbidi pakzadi2006@gmail.com 10031947532846002064 10031947532846002064 No Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam Ali Hemahian r.azizian65@yahoo.com 10031947532846002065 10031947532846002065 No Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam Sobhan Ghafourian mohamadi.sattar@yahoo.com 10031947532846002066 10031947532846002066 No Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam Iraj Pakzad pakzadi2006@gmail.com 10031947532846002067 10031947532846002067 Yes Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam