Journal of Basic Research in Medical Sciences
مجله ی تحقیقات پایه در علوم پزشکی
Journal of Basic Research in Medical Sciences
Medical Sciences
http://jbrms.medilam.ac.ir
1
admin
2383-0506
2383-0972
doi
en
jalali
1399
6
1
gregorian
2020
9
1
7
4
online
1
fulltext
en
Evaluation of chemical composition and antimicrobial activities of Scrophularia striata essential oil on dental caries pathogens
Microbiology
Microbiology
پژوهشي
Research
<div><strong>Introduction: </strong>Oral diseases are among the most important worldwide infectious diseases. Due to drug resistance and the side effects of chemical drugs, the use of herbal medicines has increased. <em>Scrophularia striata </em>(<em>S. striata</em>)<em> is</em> a herbal flowering plant that is used in microbial infections. Therefore, this study aimed to evaluate the antimicrobial activity of <em>S. striata</em> essential oil on dental carrier’s pathogens.<br>
<strong>Materials and Methods:</strong> In this study, <em>S. striata</em> essential oil was prepared and its antimicrobial activity was evaluated by disk diffusion, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) methods on dental caries pathogens <em>Streptococcus mutans </em>(<em>S. mutans</em>), <em>Lactobacillus rhamnosus </em>(<em>L. rhamnosus</em>), <em>Actinomyces viscosus </em>(<em>A. viscosus</em>), and <em>Candida albicans </em>(<em>C. albicans</em>). Moreover, the chemical composition of <em>S. striata</em> essential oil was evaluated by gas chromatography-mass spectrometry (GC-MS) method.<br>
<strong>Results:</strong> Our results showed that the most antibacterial activity of <em>S. striata </em>essential oil was related to <em>A. viscosus </em>(22.9 mm), <em>L. rhamnosus </em>(21.7 mm), and <em>S. mutans</em> (16.9 mm) essential oil showed a low antifungal activity against <em>C. albicans</em>. The dominant chemical composition of <em>S. striata </em>essential oil was terpens (39.8%).<br>
<strong>Conclusion:</strong> In general, <em>S. striata </em>essential oil has an appropriate antibacterial activity against oral pathogens. Therefore, it can be use in pharmaceutical industry to produce antimicrobial agents against dental caries and oral infectious diseases.</div>
Dental caries Antimicrobial, Scrophularia striata, Essential oil
36
42
http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-503-1&slc_lang=en&sid=1
Shahram
Dadelahi
sh.dadelahi@gmail.com
10031947532846004120
10031947532846004120
No
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran
Farnaz
Yousefi
farnazyousefi@yahoo.com
10031947532846004121
10031947532846004121
No
Department of Microbiology, Urmia Branch, Islamic Azad University, Urmia, Iran
Parisa
Emami Golmarz
emami.parisa@yahoo.com
10031947532846004122
10031947532846004122
No
Department of Genetics, Ahar Branch, Islamic Azad University, Ahar, Iran
Elham
Taheri
elham.taheri1366@gmail.com
10031947532846004123
10031947532846004123
Yes
Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran