Journal of Basic Research in Medical Sciences
مجله ی تحقیقات پایه در علوم پزشکی
Journal of Basic Research in Medical Sciences
Medical Sciences
http://jbrms.medilam.ac.ir
1
admin
2383-0506
2383-0972
doi
en
jalali
1400
6
1
gregorian
2021
9
1
8
4
online
1
fulltext
en
The effect of circuit resistance training with 40, 60 and 80 percent of one-repetition maximum on the levels of IL-10, IL-1β and body fat percent in obese postmenopausal women
Physiology
Physiology
پژوهشي
Research
<div><strong>Introduction: </strong>Adipose tissue plays an important role in increasing systemic inflammation and exercise training result in modulating inflammation by decreasing adipose tissue. The present study aimed to investigate the effect of 12 weeks circuit resistance training with 40, 60 and 80 percent of one-repetition maximum (1RM) on the levels of IL-10, IL-1β and body fat percent in obese postmenopausal women.<span dir="RTL"></span><br>
<strong>Materials and Methods: </strong>Forty four postmenopausal women (average age of 56.07 ± 3.18 years old) randomly divided into four group (each group 11 subjects) including the control and circuit resistance training with 40 (RT40), 60 (RT60) and 80 (RT80) percentage of 1RM. Exercise training program was conducted for 12 weeks and three session per week. Blood samples collected before and after the exercise training period. The ELISA method was used to measure the levels of IL-10 and IL-1β and data analysis performed with Graphpad Prism software.<span dir="RTL"></span><br>
<strong>Results: </strong>IL-10 levels in trained groups compared to control group indicated significant increase (P < 0.05), in which the increase in RT60 (P = 0.014) and RT80 (P < 0.001) groups were also significant compared to the RT40 group. In addition, significant decrease of IL-1β in RT40 (P = 0.003), RT60 (P < 0.001) and RT80 (P < 0.001) groups compared to control group were observed, as such, IL-1β decrease in RT80 group compared to RT40 (P < 0.001) and RT60 (P = 0.001) group was also significant. Moreover, different intensity circuit resistance training was associated with decrease in percent body fat (P < 0.05), which further decreases reported in the RT60 and RT80 groups.<br>
<strong>Conclusion: </strong>Despite the anti-inflammatory effects of different intensities of circuit resistance training, the higher intensity of exercise training can be associated with greater effectiveness in reducing inflammation and strengthening the anti-inflammatory pathways.</div>
Menopause, Circuit resistance training, Inflammation, Obesity, IL-10, IL-1β
13
22
http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-534-2&slc_lang=en&sid=1
Fatemeh
Sadeghi Eshtehardi
sadeghiuni@yahoo.com
10031947532846004468
10031947532846004468
No
Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran
Maghsoud
Peeri
m.peeri@iauctb.ac.ir
10031947532846004469
10031947532846004469
Yes
Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran
Mohammad Ali
Azarbayjani
azarbayjani@iauctb.ac.ir
10031947532846004470
10031947532846004470
No
Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran