Journal of Basic Research in Medical Sciences
مجله ی تحقیقات پایه در علوم پزشکی
Journal of Basic Research in Medical Sciences
Medical Sciences
http://jbrms.medilam.ac.ir
1
admin
2383-0506
2383-0972
doi
en
jalali
1400
12
1
gregorian
2022
3
1
9
2
online
1
fulltext
en
The effect of high, low and moderate intensity circuit resistance training on the levels of hepatocyte-derived fibrinogen-related protein 1 (HFREP1) and lipid profile in obese postmenopausal women
Physiology
Physiology
پژوهشي
Research
<div style="border-bottom:solid windowtext 1.0pt; border-top:solid windowtext 1.0pt; border-left:none; border-right:none; padding:1.0pt 0in 0in 0in"><span style="font-size:11pt"><span style="line-height:normal"><span style="text-autospace:none"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Introduction: </span></b><span new="" roman="" style="font-family:" times="">Different hepatokines including the <span style="color:black">hepatocyte-derived fibrinogen-related protein 1 (HFREP1)</span></span> <span new="" roman="" style="font-family:" times="">are</span> <span new="" roman="" style="font-family:" times="">secreted by liver tissue, which can affect the lipid metabolism. The aim of present study was to investigate the effect of 12 weeks circuit resistance training with different intensity on the levels of HFREP1 and lipid profile in obese postmenopausal women. </span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span style="text-autospace:none"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Materials and Methods:</span></b><span new="" roman="" style="font-family:" times=""> Subjects of the study consisted of 44 postmenopausal women with average age of 56.07 ± 3.18 years old, dividing into the circuit resistance training with low (L-RT), moderate (M-RT), high (H-RT) intensity and the control groups (11 subjects in each group). Training program was conducted for 12 weeks and three session per week. Blood samples collected in pre and post-test stages and the levels of HFREP1 were measured by ELISA method and finally data was analyzed by Graphpad Prism software.</span><span dir="RTL" style="font-family:"Times New Roman",serif" lang="FA"></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span style="text-autospace:none"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><a name="_Hlk83282040"><b><span new="" roman="" style="font-family:" times="">Results</span></b></a><b><span new="" roman="" style="font-family:" times="">:</span></b><span new="" roman="" style="font-family:" times=""> Analysis of HFREP1 data indicated that there were significant differences between different groups (P < 0.001). The results of Bonferroni post hoc-test showed that there was no significant difference between the control and L-RT groups (P > 0.05). However, HFREP1 in M-RT and H-RT groups significantly decreased compared to control group (P < 0.001). In addition, HFREP1 decrease in M-RT and H-RT groups was significant compared to L-RT group (P > 0.05). Lipid profile also improved in all trained groups, which further improvement observed in the H-RT group.</span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span style="text-autospace:none"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><a name="_Hlk85713844"><b><span new="" roman="" style="font-family:" times="">Conclusion</span></b></a><b><span new="" roman="" style="font-family:" times="">:</span></b><span new="" roman="" style="font-family:" times=""> It seems that, higher intensity circuit resistance training is associated with further decrease in the levels of HFREP1, and improving the lipid profile </span><span new="" roman="" style="font-family:" times="">can be attributed partly to downregulation of HFREP-1 levels.</span><span dir="RTL" style="font-family:"Times New Roman",serif" lang="FA"></span></span></span></span></span></span></div>
Menopause, Circuit resistance training, Hepatokines, HFREP1
61
70
http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-534-6&slc_lang=en&sid=1
Seyedeh Elham
Hashemi Jokar
hashemielham77@yahoo.com
10031947532846004950
10031947532846004950
No
Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran
Maghsoud
Peeri
m.peeri@iauctb.ac.ir
10031947532846004951
10031947532846004951
Yes
Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran
Mohammad Ali
Azarbayjani
m_azarbayjani@iauctb.ac.ir
10031947532846004952
10031947532846004952
No
Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran