en پژوهشي Research <span style="font-size:9pt"><span minion="" pro="" style="font-family:"><b>Introduction</b>: Fetuin A and B are hepatokines linked to obesity and metabolic disorders. The present study aimed to investigate the effect of 12 weeks of intermittent resistance training combined with Algomed (Chlorella vulgaris) supplementation on plasma levels of fetuin A and B in obese men.</span></span><br> <span style="font-size:9pt"><span minion="" pro="" style="font-family:"><b>Materials & Methods</b><b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">: </span></span></b>This quasi-experimental study included 44 obese men (BMI > 30), aged 23&ndash;32 years, randomly assigned to four groups (n = 11 each): control, resistance training, Algomed supplementation, and resistance training + Algomed. The training protocol was performed three times per week for 12 weeks. The supplement groups received 1800 mg/day of Algomed. Plasma levels of fetuin A and B were measured by ELISA before and after the intervention. Baseline differences were assessed using one-way ANOVA. Within-group changes were analyzed using paired t-tests, and between-group comparisons of post-test values were conducted using ANCOVA with initial values as covariates. Bonferroni post hoc tests were applied where appropriate (p < 0.05).<span lang="FA" dir="RTL" style="font-family:"Times New Roman","serif""></span></span></span><br> <span style="font-size:9pt"><span minion="" pro="" style="font-family:"><b>Results</b><b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">: &nbsp;</span></span></b>ANCOVA results showed significant differences in post-test levels of both fetuin A and fetuin B between the groups (p < 0.0001). Post hoc analysis indicated that the training + Algomed group had significantly lower fetuin-A levels compared to the control group. Furthermore, fetuin-B levels were significantly reduced in all intervention groups compared to the control, with the greatest reduction observed in the training + Algomed group compared to all other groups (p < 0.0001).</span></span><br> <span style="font-size:9pt"><span minion="" pro="" style="font-family:"><b>Conclusion</b><b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">: &nbsp;</span></span></b>Twelve weeks of intermittent resistance training combined with Algomed supplementation had a synergistic effect in reducing plasma levels of fetuin A and B in obese men. These findings suggest potential metabolic benefits for this combined intervention strategy.</span></span><br> &nbsp; Resistance Training, Plasma, Men, Obesity 64 74 http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-719-4&slc_lang=en&sid=1 Mohammad Mahdi Madani Gholamiman@yahoo.com 10031947532846008302 10031947532846008302 No Department of professional Physical Education and Sports Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran Hossein Abednatanzi abednazari@gmail.com 10031947532846008303 10031947532846008303 Yes Department of professional Physical Education and Sports Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran Mandana Gholami 10031947532846008304 10031947532846008304 No Department of professional Physical Education and Sports Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran Farshad Ghazalian 10031947532846008305 10031947532846008305 No Department of professional Physical Education and Sports Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran