en Medical genetics Medical genetics مقالات مروری Narrative review <span style="font-size:11pt"><span style="line-height:150%"><span sans-serif="" style="font-family:Calibri,"><span style="font-size:10.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">This paper delves into the ground-breaking role of MicroRNA in forecasting cancer, focusing particularly on breast cancer. MicroRNAs, tiny non-coding RNA molecules, govern gene expression and have surfaced as encouraging biomarkers for cancer prognosis. Traditional approaches to breast cancer forecasting, like mammography and genetic testing, come with constraints in accuracy and sensitivity. MicroRNA-dependent prognostication techniques present benefits, such as stability in bodily fluids, tissue-specific expression patterns, and the potential for non-invasive testing. These techniques can enhance precision, sensitivity, and specificity, resulting in timely detection and personalized treatment plans. Despite the promising outlook for MicroRNA in cancer prognosis, obstacles like standardization of detection techniques and ethical dilemmas require attention.</span></span></span> <span style="font-size:10.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Scopus, PubMed and, Web of Science databases were used, and articles were extracted and reviewed using the keywords microRNA, Breast Cancer, Prediction. The paper concludes that MicroRNA is poised to assume a pivotal role in the timely identification and efficient management of cancer, heralding a new age of tailored medicine</span></span></span><span dir="RTL" lang="FA" style="font-size:10.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">.</span></span></span><span style="font-size:10.0pt"><span style="line-height:150%"><span style="font-family:"Times New Roman","serif""></span></span></span></span></span></span><br> <br> <br> &nbsp; microRNA, Breast Cancer, Prediction 11 20 http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-840-1&slc_lang=en&sid=1 Maryam Kheiry m.kheiry@yahoo.com 10031947532846007449 10031947532846007449 No Non-Communicable Diseases Research Center, Ilam University of Medical sciences, Ilam, Iran. Farajolah Maleki 10031947532846007450 10031947532846007450 Yes Clinical Research Development Unit, Shahid Mostafa Khomeini hospital, Ilam university of medical sciences, Ilam, Iran.