en گزارش مورد Case report <br> <span style="font-size:9pt"><span minion="" pro="" style="font-family:"><b>Introduction</b>: Marfan syndrome (MFS) is a connective tissue disorder with multisystem involvement, including cardiovascular and ocular complications, which can impact a patient&rsquo;s work capacity. While MFS may necessitate certain job restrictions, complete exclusion from professional roles may not be justified. Adjustments and careful planning can enable individuals with MFS to maintain meaningful employment within safe parameters.</span></span><br> <span style="font-size:9pt"><span minion="" pro="" style="font-family:"><b>Case Report</b><b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">: </span></span></b>This case examines a 29-year-old male patient diagnosed with MFS, presenting with ocular issues and significant cardiovascular involvement, including aortic insufficiency and a history of valve replacement. Given his condition, ongoing anticoagulant therapy with warfarin is required, alongside annual cardiac assessments. Employment restrictions recommended for this patient include avoiding heavy manual labor, working at heights, operating hazardous tools, confined workspaces, and solitary work environments. Additionally, prescription glasses are mandatory to address his ocular complications, with regular follow-up by an ophthalmologist. Following a sleep study, no limitations were indicated for night shift work, permitting him flexibility in shift scheduling.</span></span><br> <span style="font-size:9pt"><span minion="" pro="" style="font-family:"><b>Conclusion</b><b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">: &nbsp;</span></span></b>This case highlights that while patients with MFS can remain active in professional roles, individualized work modifications are essential. Work-related precautions, especially concerning physically demanding tasks and hazardous environments, should align with the patient&rsquo;s medical condition and treatment. Personalized occupational health assessments can enhance safety and facilitate work participation for individuals with MFS.</span></span><br> &nbsp; Marfan Syndrome, Occupational Health, Occupational Diseases 75 82 http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-893-1&slc_lang=en&sid=1 Negin Kassiri neginkassiri@gmail.com 10031947532846008277 10031947532846008277 Yes Occupational Medicine Research Center, Iran University of Medical Sciences, Tehran, Iran Leila Khedmati Hampa leyla.hampa2019@gmail.com 10031947532846008278 0009-0004-6595-227X No Department of Occupational Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran Siamak Saber drsiamaksaber@gmail.com 10031947532846008279 10031947532846008279 No Bion Medical Genetic Laboratory, Muscat, Oman Sepideh Lamei Haghighat sepideh.lamei@gmail.com 10031947532846008280 10031947532846008280 No Department of Occupational Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran Somaye Nejabat Ghamsari somaye.nejabat1992@gmail.com 10031947532846008281 0009000343670004 No Department of Occupational Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran