en Gastroenterology Gastroenterology پژوهشي Research <span style="font-size:9pt"><span style="font-family:&quot;Minion Pro&quot;,serif"><b>Introduction</b>: Evaluating the level of kidney, liver, coagulation, and blood diagnostic markers in cirrhosis and hepatitis patients can help in early diagnosis, timely treatment, and prevention of complications of these diseases.</span></span><br> <span style="font-size:9pt"><span style="font-family:&quot;Minion Pro&quot;,serif"><b>Materials & Methods</b><b><span style="font-size:11.0pt"><span style="font-family:&quot;Times New Roman&quot;,serif">: </span></span></b>This study is an analytical cross-sectional study. After obtaining the necessary permits by referring to the medical records department of Abadan and Khorramshahr educational hospitals, the information of patients (148 patients) with liver cirrhosis and hepatitis admitted from March 21, 2017, to March 19, 2020, available in the HIS, was obtained. Patient data was analysed using IBM SPSS software (version 16). Data compared means among study groups using t-tests and two-way ANOVA. A p-value < 0.05 was considered statistically significant.<span lang="FA" dir="RTL" style="font-family:&quot;Times New Roman&quot;,serif"></span></span></span><br> <span style="font-size:9pt"><span style="font-family:&quot;Minion Pro&quot;,serif"><b>Results</b><b><span style="font-size:11.0pt"><span style="font-family:&quot;Times New Roman&quot;,serif">: &nbsp;</span></span></b>In both diseases, the mean levels of Hb and Hct were lower than the normal range, while the mean of FBS, total and direct bilirubin, AST, ALT, ALP, PT, and INR were higher than the normal range. Comparing the markers between liver cirrhosis and hepatitis, the mean levels of BS, FBS, BUN, and creatinine were significantly higher in cirrhosis. The means of LDL, Na, direct and total bilirubin, AST, and ALT were significantly higher in hepatitis.</span></span><br> <span style="font-size:9pt"><span style="font-family:&quot;Minion Pro&quot;,serif"><b>Conclusion</b><b><span style="font-size:11.0pt"><span style="font-family:&quot;Times New Roman&quot;,serif">: &nbsp;</span></span></b>According to the research, cirrhosis tends to occur at an older age than hepatitis. Both diseases are more prevalent among men. In cirrhosis, mean blood sugar and renal markers (creatinine and BUN) were significantly higher than in hepatitis. Liver diagnostic markers (direct and total bilirubin, AST, and ALT) and LDL were significantly higher in hepatitis than in cirrhosis.</span></span><br> &nbsp; Hepatitis, Liver Cirrhosis, Biomarkers 1 11 http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-686-2&slc_lang=en&sid=1 Mehdi Kiani Motlagh Jonaghani mehdi.kiani77@yahoo.com 10031947532846008087 0009-0000-1487-2318 No Student Research Committee, Abadan University of Medical Sciences, Abadan, Iran Atefeh Zahedi atefe.zahedi@gmail.com 10031947532846008088 10031947532846008088 No Department of Public Health, Asadabad School of Medical Sciences, Asadabad, Iran Hoda Mojiri-Forushani dr.mojiri@yahoo.com 10031947532846008089 10031947532846008089 No Department of Pharmacology, School of Medicine Abadan, University of Medical Sciences, Abadan, Iran Khadijeh Kanani khadijekanani@gmail.com 10031947532846008090 10031947532846008090 No Clinical Research Development Unit, Taleghani Educational Hospital, Abadan University of Medical Sciences, Abadan, Iran Sara Mobarak dr.mobarak92@gmail.com 10031947532846008091 10031947532846008091 No Department of Infectious Diseases, School of Medicine, Abadan University of Medical Sciences, Abadan, Iran Esmat Radmanesh esmatradmanesh33@gmail.com 10031947532846008092 10031947532846008092 Yes Department of Physiology, School of Medicine, Abadan University of Medical Sciences, Abadan, Iran