Journal of Basic Research in Medical Sciences
J Basic Res Med Sci
Volume 12, Issue 3 (5-2025)
jbrms 2025, 12(3): 75-82 |
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Kassiri N, Khedmati Hampa L, Saber S, Lamei Haghighat S, Nejabat Ghamsari S. Work adjustment in patients with Marfan syndrome: A case report. jbrms 2025; 12 (3) :75-82
URL: http://jbrms.medilam.ac.ir/article-1-886-en.html
URL: http://jbrms.medilam.ac.ir/article-1-886-en.html
Negin Kassiri 
, Leila Khedmati Hampa , Siamak Saber , Sepideh Lamei Haghighat , Somaye Nejabat Ghamsari
, Leila Khedmati Hampa , Siamak Saber , Sepideh Lamei Haghighat , Somaye Nejabat Ghamsari
Occupational Medicine Research Center, Iran University of Medical Sciences, Tehran, Iran , neginkassiri@gmail.com
Abstract: (26 Views)
Introduction: Marfan syndrome (MFS) is a connective tissue disorder with multisystem involvement, including cardiovascular and ocular complications, which can impact a patient’s work capacity. While MFS may necessitate certain job restrictions, complete exclusion from professional roles may not be justified. Adjustments and careful planning can enable individuals with MFS to maintain meaningful employment within safe parameters.
Case Report: This case examines a 29-year-old male patient diagnosed with MFS, presenting with ocular issues and significant cardiovascular involvement, including aortic insufficiency and a history of valve replacement. Given his condition, ongoing anticoagulant therapy with warfarin is required, alongside annual cardiac assessments. Employment restrictions recommended for this patient include avoiding heavy manual labor, working at heights, operating hazardous tools, confined workspaces, and solitary work environments. Additionally, prescription glasses are mandatory to address his ocular complications, with regular follow-up by an ophthalmologist. Following a sleep study, no limitations were indicated for night shift work, permitting him flexibility in shift scheduling.
Conclusion: This case highlights that while patients with MFS can remain active in professional roles, individualized work modifications are essential. Work-related precautions, especially concerning physically demanding tasks and hazardous environments, should align with the patient’s medical condition and treatment. Personalized occupational health assessments can enhance safety and facilitate work participation for individuals with MFS.
Type of Study: Case report |
Received: 2024/08/25 | Accepted: 2024/10/23 | Published: 2025/05/11
Received: 2024/08/25 | Accepted: 2024/10/23 | Published: 2025/05/11
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