[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
About Journal::
Editorial Board::
Articles Archive::
Indexing Databases::
To Authors::
To Reviewers::
Submit Your Article::
Policies and Publication Ethics::
Archiving Policy::
Site Facilities::
Contact Us::
Google Scholar Metrics

Citation Indices from GS

AllSince 2019
Search in website

Advanced Search
Receive site information
Enter your Email in the following box to receive the site news and information.
Registered in



:: Volume 7, Issue 2 (3-2020) ::
2020, 7(2): 7-12 Back to browse issues page
The patterns of aminoglycoside and fluoroquinolones resistance among uropathogenic Escherichia coli isolates
Saeed Hemati , Morteza Shams , Arash Rahmatian , Hasan Nourmohammadi , Amir Abdoli , Farajolah Maleki , Ghasem Talee , Zahra Mahdavi , Elham Bastani , Vahid Hatami , Fatemeh Kohzadi
Zoonotic Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran
Abstract:   (1789 Views)
Introduction: In the study we sought to determine the patterns of regional antibiotic resistances among uropathogenic Escherichia coli (UPEC) isolates. Our finding could be useful for better recognition of regional antibiotic resistances and scheduling a program to control this condition.
Materials and methods: In the study, 270 nonduplicate UPEC isolates were examined from urine samples of outpatients with urinary tract infections (UTIs). All isolates were identified by gram staining and standard conventional biochemical tests. Antimicrobial susceptibility test was performed by disk diffusion (Kirby–Bauer) method. The commercial antibiotics disks (PADTAN TEB Co., Iran) were applied in the study, included amikacin (30 μg), gentamycin (10 μg), ciprofloxacin (5 μg), and nalidixic acid (30 μg).
Results: Most of the patients were female (221, 81.9%). The highest resistance was observed for nalidixic acid (56%), followed by ciprofloxacin 39.64%. In contrast, the lowest resistance was seen for amikacin (3.90%) and gentamicin (10.04%). Moreover, 19.62% of the isolates were multidrug-resistant (MDR).
Conclusion: Amikacin and gentamicin could be chosen as first line antibiotics in treatment of UTIs. Continuous monitoring studies recommended for acquire a suitable regional antibiotic resistance pattern.
Keywords: Escherichia coli, UTIs, Antimicrobial susceptibility
Full-Text [PDF 464 kb]   (785 Downloads)    
Type of Study: Research | Subject: Microbiology
Received: 2020/02/11 | Accepted: 2020/05/26 | Published: 2020/03/1
Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Hemati S, Shams M, Rahmatian A, Nourmohammadi H, Abdoli A, Maleki F, et al . The patterns of aminoglycoside and fluoroquinolones resistance among uropathogenic Escherichia coli isolates. Journal of Basic Research in Medical Sciences 2020; 7 (2) :7-12
URL: http://jbrms.medilam.ac.ir/article-1-483-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 7, Issue 2 (3-2020) Back to browse issues page
مجله ی تحقیقات پایه در علوم پزشکی Journal of Basic Research in Medical Sciences
Persian site map - English site map - Created in 0.2 seconds with 41 queries by YEKTAWEB 4657