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:: Volume 7, Issue 4 (9-2020) ::
2020, 7(4): 36-42 Back to browse issues page
Evaluation of chemical composition and antimicrobial activities of Scrophularia striata essential oil on dental caries pathogens
Shahram Dadelahi , Farnaz Yousefi , Parisa Emami Golmarz , Elham Taheri
Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran , elham.taheri1366@gmail.com
Abstract:   (1648 Views)
Introduction: Oral diseases are among the most important worldwide infectious diseases. Due to drug resistance and the side effects of chemical drugs, the use of herbal medicines has increased. Scrophularia striata (S. striata) is a herbal flowering plant that is used in microbial infections. Therefore, this study aimed to evaluate the antimicrobial activity of S. striata essential oil on dental carrier’s pathogens.
Materials and Methods: In this study, S. striata essential oil was prepared and its antimicrobial activity was evaluated by disk diffusion, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) methods on dental caries pathogens Streptococcus mutans (S. mutans), Lactobacillus rhamnosus (L. rhamnosus), Actinomyces viscosus (A. viscosus), and Candida albicans (C. albicans). Moreover, the chemical composition of S. striata essential oil was evaluated by gas chromatography-mass spectrometry (GC-MS) method.
Results: Our results showed that the most antibacterial activity of S. striata essential oil was related to A. viscosus (22.9 mm), L. rhamnosus (21.7 mm), and S. mutans (16.9 mm) essential oil showed a low antifungal activity against C. albicans. The dominant chemical composition of S. striata essential oil was terpens (39.8%).
Conclusion:  In general, S. striata essential oil has an appropriate antibacterial activity against oral pathogens. Therefore, it can be use in pharmaceutical industry to produce antimicrobial agents against dental caries and oral infectious diseases.
Keywords: Dental caries Antimicrobial, Scrophularia striata, Essential oil
Full-Text [PDF 223 kb]   (746 Downloads)    
Type of Study: Research | Subject: Microbiology
Received: 2020/04/20 | Accepted: 2020/07/11 | Published: 2020/09/19
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Dadelahi S, Yousefi F, Emami Golmarz P, Taheri E. Evaluation of chemical composition and antimicrobial activities of Scrophularia striata essential oil on dental caries pathogens. Journal of Basic Research in Medical Sciences 2020; 7 (4) :36-42
URL: http://jbrms.medilam.ac.ir/article-1-519-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 7, Issue 4 (9-2020) Back to browse issues page
مجله ی تحقیقات پایه در علوم پزشکی Journal of Basic Research in Medical Sciences
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