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:: Volume 8, Issue 4 (9-2021) ::
2021, 8(4): 60-70 Back to browse issues page
Effects of aerobic training and omega-3 supplementation on the levels of CRP, MDA and lipid profile in overweight and obese women
Shila Montazer , Mandana Gholami , Mohammad Ali Azarbayjani , Hossein Abed Natanzi
Department of Physical Education and Sport Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran , shilamontazer@gmail.com
Abstract:   (1313 Views)
Introduction: Exercise training and omega 3 supplements play an important role in modulating the levels of oxidative and inflammatory mediators. The present study conducted aimed to investigate the effects of aerobic training and omega-3 supplementation on the levels of oxidative (MDA) and inflammatory (CRP) mediators and lipid profile in overweight and obese women.
Materials and Methods: The 40 overweight and obese women (BMI = 29.1 ± 6.9 kg/m2) randomly assigned to four groups (10 subjects in each group) including placebo (C), omega-3 (S), training (T) and training + omega 3 (ST) groups. Aerobic training program was performed with 50-70 percent of maximum heart rate for eight weeks/three sessions per week. Daily 2000 mg omega 3 supplement were also consumed by S and ST groups. The MDA, CRP and lipid profile levels were measured and data were analyzed by SPSS software (version 24).
Results: Significant decrease in CRP levels in S (P = 0.014), T (P = 0.030) and ST (P < 0.001) groups compared to C group, and significant decrease in MDA levels in T and ST groups compared to C and S groups were observed (P < 0.05). In addition, lipid profile indicated a significant improvement in T and ST groups (P < 0.05).
Conclusion: Despite the aerobic training and training + omega-3 supplement effects in decreasing levels of CRP, MDA and lipid profile improvement, no significant difference was observed between the two groups. It seems that, eight weeks omega-3 ingestion along with aerobic training don’t exert a synergistic effect.
Keywords: Aerobic training, Inflammation, Oxidative stress, Omega-3
Full-Text [PDF 290 kb]   (556 Downloads)    
Type of Study: Research | Subject: Physiology
Received: 2020/04/3 | Accepted: 2020/07/16 | Published: 2021/09/19
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Montazer S, Gholami M, Azarbayjani M A, Abed Natanzi H. Effects of aerobic training and omega-3 supplementation on the levels of CRP, MDA and lipid profile in overweight and obese women. Journal of Basic Research in Medical Sciences 2021; 8 (4) :60-70
URL: http://jbrms.medilam.ac.ir/article-1-581-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 8, Issue 4 (9-2021) Back to browse issues page
مجله ی تحقیقات پایه در علوم پزشکی Journal of Basic Research in Medical Sciences
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