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:: Volume 9, Issue 3 (6-2022) ::
2022, 9(3): 42-50 Back to browse issues page
Effect of eight weeks combined training and Zataria multiflora supplement on the levels of IL-1β and insulin resistance in overweight and obese men
Alireza Jadid , Mandana Gholami , Hossein Abed Natanzi
Department of Physical Education and Sport Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran , m.gholami@srbiau.ac.ir
Abstract:   (680 Views)
Introduction: The anti-inflammatory effects of exercise training and zataria multiflora have been proven. In the present study, researcher investigated the effect of eight weeks combined exercise training and Zataria multiflora (Z. multiflora) supplement on the levels of IL-1β and insulin resistance in overweight and obese men.
Materials and Methods: The 40 overweight and obese men with average age of 27.73 ± 2.15 years old and average body mass index (BMI) 28.41 ± 1.75 kg/m2 were randomly divided into four groups including the placebo, Z. multiflora, combined training, and training + Z. multiflora. Combined exercise training program conducted for eight weeks and three sessions per week. Z. multiflora supplement was also consumed at 500 mg daily. Blood sampling was performed before and 48 hours after the eight weeks intervention. The levels of IL-1β and insulin were measured by ELISA method. Data were analyzed by analysis of covariance and Bonferroni post hoc test.
Results: The levels of IL-1β in training and training + Z. multiflora groups significantly decreased compared to placebo and Z. multiflora groups (P < 0.001). In addition, significant decrease of insulin resistance in training group compared to placebo (P < 0.001) and Z. multiflora (P = 0.003) groups, and also in training + Z. multiflora group compared to placebo and Z. multiflora groups were observed (P < 0.001).
Conclusion: Combined training alone or in combination with Z. multiflora supplementation can exert anti-inflammatory effects. Moreover, Z. multiflora supplementation cause the relative increase in exercise training effect for decrease in IL-1β and insulin resistance.
 
Keywords: Exercise Training, Zataria Multiflora, Inflammation, Cytokine
Full-Text [PDF 322 kb]   (284 Downloads)    
Type of Study: Research | Subject: Public health
Received: 2021/02/2 | Accepted: 2021/05/24 | Published: 2022/06/19
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Jadid A, Gholami M, Abed Natanzi H. Effect of eight weeks combined training and Zataria multiflora supplement on the levels of IL-1β and insulin resistance in overweight and obese men. Journal of Basic Research in Medical Sciences 2022; 9 (3) :42-50
URL: http://jbrms.medilam.ac.ir/article-1-603-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 9, Issue 3 (6-2022) Back to browse issues page
مجله ی تحقیقات پایه در علوم پزشکی Journal of Basic Research in Medical Sciences
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