[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 5, Issue 2 (3-2018) ::
JBRMS 2018, 5(2): 48-55 Back to browse issues page
Antifungal agents: Polyene, azole, antimetabolite, other and future agents
Fardin Ali Malayeri , Aliakbar Rezaei , Omid Raiesi
phD Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran , omid_raissi69@yahoo.com
Abstract:   (247 Views)
Antifungals have always been considered as one of the astonishing discoveries of the 20th century. This is correct, but the real marvel is the development of antifungal resistance in hospitals, communities, and the environment concomitant with their use. Fungal infections have emerged as an important clinical threat, with significant associated morbidity and mortality.  This study is designed to provide a comprehensive view of antifungal agents and related agents. Information was based on the expertise of some literatures. Over the past decades, the incidence and diversity of fungal infection has grown in association with an increasing number of immunocompromised patients. An understanding of the pharmacokinetic and pharmacodynamics properties of the classes of antifungal compounds is vital for the effective management of invasive fungal infections. This review provides a summary of the pharmacologic principles involved in treatment of fungal diseases.  Clinical needs for novel antifungal agents have altered steadily with the rise and fall of AIDS-related mycoses, and the change in spectrum of fatal disseminated fungal infections that has accompanied change in therapeutic immunosuppressive therapies.
Keywords: Antifungal agents, Future agents, Polyenes, Azole
Full-Text [PDF 677 kb]   (124 Downloads)    
Type of Study: Review Article | Subject: Pharmacology
Received: 2017/12/30 | Accepted: 2018/04/14 | Published: 2018/04/21
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA code



XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ali Malayeri F, Rezaei A, Raiesi O. Antifungal agents: Polyene, azole, antimetabolite, other and future agents. JBRMS. 2018; 5 (2) :48-55
URL: http://jbrms.medilam.ac.ir/article-1-362-en.html


Volume 5, Issue 2 (3-2018) Back to browse issues page
مجله ی تحقیقات پایه در علوم پزشکی Journal of Basic Research in Medical Sciences
Persian site map - English site map - Created in 0.23 seconds with 31 queries by YEKTAWEB 3735