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:: Volume 7, Issue 3 (6-2020) ::
2020, 7(3): 62-70 Back to browse issues page
Neutrophil-to-lymphocyte ratio as a novel and valuable marker for assessing disease severity in Ulcerative colitis, Multiple sclerosis, and Kawasaki disease: A review
Alireza Ghodsi , Mohammad Mobin Mirimoghaddam , Mehrdad Sarabi , Amirreza Dehghan Tarazjani , Alireza Omranzadeh , Masoud Mahdavi Rashed , Hamid Reza Rahimi
Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran , rahimihamidrezaa@gmail.com
Abstract:   (2087 Views)
Ulcerative colitis (UC), multiple sclerosis (MS), and Kawasaki disease (KD) are three autoimmune diseases that involve the colon mucosa, myelin of the central nervous system neurons, and vascular epithelium. All these diseases need invasive, expensive, and complex modalities or criteria in order to monitor the disease severity. Recently, the neutrophil-to-lymphocyte ratio (NLR) has been proposed as a valuable, cheap, and easy marker of systemic inflammation. As all the above-mentioned diseases involve neutrophils and lymphocytes as the two major cell lines, it may be applicable to assess their severity according to the NLR. Here, we review the available literature with this regard.
Keywords: Neutrophil to lymphocyte ratio, Ulcerative colitis, Multiple sclerosis, Kawasaki disease
Full-Text [PDF 258 kb]   (922 Downloads)    
Type of Study: Review Article | Subject: Immunology
Received: 2020/04/13 | Accepted: 2020/07/27 | Published: 2020/06/12
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Ghodsi A, Mirimoghaddam M M, Sarabi M, Dehghan Tarazjani A, Omranzadeh A, Mahdavi Rashed M et al . Neutrophil-to-lymphocyte ratio as a novel and valuable marker for assessing disease severity in Ulcerative colitis, Multiple sclerosis, and Kawasaki disease: A review. Journal of Basic Research in Medical Sciences 2020; 7 (3) :62-70
URL: http://jbrms.medilam.ac.ir/article-1-527-en.html


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Volume 7, Issue 3 (6-2020) Back to browse issues page
مجله ی تحقیقات پایه در علوم پزشکی Journal of Basic Research in Medical Sciences
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