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:: Volume 11, Issue 1 (1-2024) ::
2024, 11(1): 79-85 Back to browse issues page
Are bacterial persister cells really the cause of infection relapse/recalcitrance?
Behrooz Sadeghi Kalani , Parisa Asadollahi
Department of Microbiology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran - Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran , asadolahi.p@gmail.com
Abstract:   (243 Views)
Introduction: Looking into the literature, many articles accuse bacterial persister cells as important causes of infection relapse/recalcitrance. This opinion paper, highlights the knowledge gaps and scientific misconceptions in experimental procedures regarding the role of persisters in relapse/recalcitrance of infections and recommends a roadmap for investigations in this field.
Conclusion:  It is debated in this paper, that unless the queries and missing points are addressed clearly, persisters cannot be stigmatized as the culprit of infection relapse/recalcitrance.
Keywords: Persister cells, Bacteria, Relapse, Recalcitrance, Infection
Full-Text [PDF 801 kb]   (82 Downloads)    
Type of Study: Research | Subject: Microbiology
Received: 2023/12/16 | Accepted: 2024/01/29 | Published: 2024/01/20
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Sadeghi Kalani B, Asadollahi P. Are bacterial persister cells really the cause of infection relapse/recalcitrance?. Journal of Basic Research in Medical Sciences 2024; 11 (1) :79-85
URL: http://jbrms.medilam.ac.ir/article-1-803-en.html

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Volume 11, Issue 1 (1-2024) Back to browse issues page
مجله ی تحقیقات پایه در علوم پزشکی Journal of Basic Research in Medical Sciences
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